West Memphis is the largest city in Crittenden County, Arkansas, United States. The population was 24,520 at the 2020 census, ranking it as t…West Memphis is the largest city in Crittenden County, Arkansas, United States. The population was 24,520 at the 2020 census, ranking it as the state's 20th largest city. It is part of the Memphis metropolitan area, and is located directly across the Mississippi River from Memphis, Tennessee.