In their Week 11 matchup on Sunday at 4:05 PM ET, RB Isaac Guerendo and the San Francisco 49ers square off against the ...

ANALYSIS: San Francisco 49ers running back Isaac Guerendo has barely seen the field as a rookie. He is the RB63 for the year, ...

San Francisco 49ers rookie running back Isaac Guerendo’s coachability and maturity has played a big role in his steady ...

San Francisco 49ers running back Christian McCaffrey is set to make his season debut on Sunday against the Tampa Bay ...

Since joining the 49ers, Isaac Guerendo's rise to significant snaps came in the wake of injuries to star running backs Christian McCaffrey, Elijah ...

San Francisco 49ers running back Isaac Guerendo joined the 49ers "You've Got Mail" podcast presented by Delta Dental to ...

San Francisco 49ers running back Isaac Guerendo has looked like one of the most explosive backs in the NFL in his limited ...

There's no such thing as having too many running backs. Just ask the San Francisco 49ers. Jordan Mason, who is starting in ...

Rookie running back Isaac Guerendo also shined with 85 yards on 14 carries and his first career touchdown after Jordan Mason exited the game early with a shoulder injury. Wide receiver Deebo ...

Matthew Berry, Jay Croucher, and Connor Rogers highlight their top running back waiver wire adds Week 10, including Jaylen ...

In Week 10, running back Isaac Guerendo and the San Francisco 49ers' rushing attack will square off against the Tampa Bay ...