Bill Maher wrapped up the season of Real Time with multiple tense exchanges with Neil deGrasse Tyson on Democrats losing the election and transgender athletes.

The clash between Maher and Tyson comes at a time of tense debate in Washington D.C. surrounding the transgender community. Sen. John Fetterman, D-Pa., last week offered to allow Rep.-elect Sarah McBride, D-Del., to use his private office bathroom after multiple Republican lawmakers spoke out against her use of the women's facilities.

A heated clash over biological differences sparks a broader conversation about science, fairness, and perception.

Bill Maher and astrophysicist Neil deGrasse Tyson have a fiery exchange after the scientist questioned a claim about the biological differences between men and women in sports.

Robby Soave and Niall Stanage react to Bill Maher and scientist Neil deGrasse Tyson bickering over why Democrats lost the election.