The San Francisco 49ers will be without their starting quarterback and their best defensive player when they visit the Green ...

The San Francisco 49ers will be missing two of their best players in their must-win matchup against the Green Bay Packers ...

The Week 12 injury report is an extremely demoralizing one for the San Francisco 49ers. First, it was Brock Purdy who was ruled out with a shoulder injury. Now, ...

The 49ers have allowed 222 points, or 22.2 points per game, tied for 16th. Last year, the defense allowed 298 points, or 17.5 ...

San Francisco 49ers star edge rusher Nick Bosa left Sunday's game with an injury before the Seahawks rallied to win the NFC ...

Brandon Allen will start in place of an injured Brock Purdy when the 49ers (5-5) also have to play without Nick Bosa on ...

San Francisco 49ers quarterback Brock Purdy will miss Sunday's game against the Green Bay Packers with a sore throwing ...

On Friday, the Niners announced Bosa would be OUT for their game against the Green Bay Packers. Joining him on the sideline ...

Bosa (hip/oblique) has been ruled out ahead of Sunday's matchup against the Packers, Cam Inman of The San Jose Mercury News reports. Bosa didn't practice all week after sustaining hip and oblique ...

San Francisco 49ers head coach Kyle Shanahan announced that the team has ruled out quarterback Brock Purdy for Sunday's ...

Brock Purdy and Nick Bosa are not available for the San Francisco 49ers when they enter Green Bay with designs on finding ...

Big news and not good news out of the Bay Area on Friday. The 5-5 San Francisco 49ers will be in Green Bay on Sunday to play ...