After only playing in four games last season, McCaffrey is aiming to make a massive comeback to help get the Niners back in ...

Most of the San Francisco 49ers' starters watched from the sidelines during last weekend's preseason opener against the ...

A revitalized Christian McCaffrey took the ball on the 49ers’ opening play and was off and running in a heavy workload ...

HENDERSON, Nev. — Outside of a few brief skirmishes, the Las Vegas Raiders and San Francisco 49ers were on good behavior ...

No starters on the San Francisco 49ers, except for left guard Ben Bartch, played in the first preseason game against the Denver Broncos. The 49ers don't usually ...

49ers rookie defensive tackle CJ West had to leave Thursday’s practice after hurting his knee, but it doesn’t appear to be a ...

San Francisco 49ers rookie defensive tackle CJ West suffered a scare during Thursday's joint practice with the Las Vegas ...

The 49ers have continued to deal with injuries on the offensive side of the ball, this time with lineman Andre Dillard.

San Francisco 49ers head coach Kyle Shanahan says Brandon Aiyuk will be ready around the one third mark of the season.

The San Francisco 49ers need their stars to bounce back if they want to return to the playoffs this year.

The 49ers don't know for sure when wide receiver Brandon Aiyuk will be ready to return from last season's knee injury.

All signs point to Aiyuk starting the season on the reserve/PUP list, which would sideline him for the first four weeks of ...