A molecule designed to activate iron locked up in organelles called lysosomes and thereby induce cell death might offer a way to tackle treatment-resistant cancer. Building on the foundation provided ...

The missing step in the formation of a lipid molecule that allows certain single-celled organisms to survive the most extreme environments on Earth has now been deciphered. The missing step in the ...

Better mRNA release inside cells boosts vaccine and gene editing performance, enabled by redesigned lipid molecules that grip ...

Our body's fat metabolism plays a vital role in energy production in our body. A research team at the University of Basel, Switzerland, has discovered a molecular switch that regulates lipid ...

Columbia researchers have found that a rare type of lipid is a key driver of ferroptosis, a form of cell death discovered by Columbia professor Brent Stockwell. The new research found that a rare type ...

Recent advancements in understanding the molecular basis of the prostaglandin D2 receptor (DP2) have significant implications for developing new anti-inflammatory and anti-allergic therapeutics. DP2, ...

Interactions between proteins and lipids have diverse and complex roles in various biological processes, ranging from the structure, function, and dynamics of biological membranes to host-pathogen ...

The body has to clear away dead cells and other unnecessary or unneeded stuff, and one mechanism that is crucial to the degradation of such materials is called LC3-associated phagocytosis (LAP). This ...

UT Southwestern researchers have discovered a molecular pathway that allows cells to sense when their lipid supplies become depleted, prompting a flurry of activity that prevents starvation. The ...

In experiments using neonatal mice, researchers have identified a fatty molecule in breast milk that triggers a process in which stem cells in the brain produce cells that create new white matter, ...