Snow and rain are in the forecast for some parts of the U.S. as travelers hit the road and head to the airport for Thanksgiving.

Stormy weather is set to bring rain and snow, which will significantly impact hundreds of millions of people who plan to travel for the Thanksgiving holiday this week.

Snow is headed to the Midwest and the West ahead of Thanksgiving, while rain will target the East Coast on Thanksgiving Day.

Travel has kicked into high gear as millions start to hit the roads and pack airports ahead of Thanksgiving. And while most people should arrive at their holiday destinations relatively stress-free, the return trip back home could be tricky for millions in the eastern half of the U.