The carving up of the amyloid precursor protein (APP) by the successive action of β- and γ-secretases liberates Aβ, but also yields a small intracellular fragment, the APP intracellular domain (AICD).
The current issue of Neuron contains a scientific debate that bears watching. It is about one of the great mysteries of amyloid-β precursor protein (APP), that is, its physiological role. Scientists ...
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Cleavage of the amyloid precursor protein (APP) at the cell surface produces extracellular amyloid-β peptides (Aβ) and the APP intracellular domain, AICD. The predominant hypotheses in the Alzheimer's ...
Dear Dr. Roach: I’m an 88-year-old female who has been diagnosed with ventricular fibrillation. My cardiac electrophysiology doctor, who implanted a conventional pacemaker four years ago, has noticed ...
*Refers to the latest 2 years of stltoday.com stories. Cancel anytime. Dr. Roach: I’m an 88-year-old female who has been diagnosed with ventricular fibrillation. My cardiac electrophysiology doctor, ...