Yale researchers have uncovered a way to make a type of white blood cells known as natural killer cells — which kill infected, damaged, or malignant cells in the body — more effective against cancer.

For years, chimeric antigen receptor (CAR) T cell therapies have led the way in cell-based immunotherapy, offering hope to many patients with certain blood cancers. But now, researchers believe the ...

Cancer immunotherapy has been transformed by engineered T cells, but those bespoke treatments are slow, expensive, and out of reach for many patients who need help quickly. A new way to generate vast ...

These findings suggest that KIR2DS2-positive (KIR2DS2+) natural killer (NK) cells could be an attractive therapeutic target for in vivo strategies, although enhanced effector function is lost during ...

CAR-NK cell therapies are innovative therapeutic options developed for the purpose of overcoming some of the limitations associated with CAR-T cell therapies, such as therapy-induced side effects.

In a study that further corroborated these observations, scientists found that cyclic fasting in mice improved their antitumor responses mediated by natural killer (NK) cells. 4 The results, published ...

Natural Killer (NK) cells are vital immune defenders that target and destroy cancer cells. However, in aging and cancer patients, NK cells often become "senescent"—losing their effectiveness due to ...