Among the cell death mechanisms addressed are: pro-apoptotic signals resulting from activation of the ER-associated kinase IRE1, an upstream activator of apoptotic signalling kinase 1 (ASK1 ...
Our work on autophagy involves determining the molecular pathways regulating autophagy during pathogen infection. Autophagy has been recently shown to be an important component of the innate immune ...
The present review discusses various theories and mechanisms behind the autophagy-dependent induction of cancer stem cell (CSC) phenotype. Given the role of autophagic functions in CSC aggressiveness ...
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