Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...

Scientists at École Polytechnique Fédérale Lausanne (EPFL), and at UNIL-CHUV, University Hospital Lausanne (CHUV) and University of Lausanne (UNIL) have developed a computational method to create ...

T cell immunotherapies are on the cutting-edge of cancer treatments, but a full understanding of how they work has been ...

A hidden “jack-in-the-box” mechanism inside T cells may hold the key to unlocking more powerful cancer immunotherapies.

Researchers from the Keck School of Medicine of USC have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response to cancer in mice—effectively ...

Plants form a critical model for understanding regulated cell death (RCD) as part of their sophisticated immune responses. In the ongoing evolutionary arms ...

Ryan Notti (left) and Thomas Walz (right) discovered new characteristics of a T cell receptor that are essential to a variety ...

Opioid receptors are a subset of G protein–coupled receptors (GPCRs). These membrane proteins transmit signals into the cell ...