Inside human cells, biology has pulled off the ultimate packing job, figuring out how to fit six feet of DNA into a nucleus ...

Cr yo-ET captured dozens of projection images of each slice from different angles. Computational processing then stitched ...

New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their ...

Using computer simulations, chemists have discovered how nuclear bodies called nucleoli interact with chromosomes in the nucleus, and how those interactions help the nucleoli exist as stable droplets ...

Nuclear pore complexes (NPCs) govern macromolecular transport between the nucleus and cytoplasm and serve as key positional markers within the nucleus. Several protein components of yeast NPCs have ...

University of Alberta researchers have found an answer to a fundamental question in genomic biology that has eluded scientists since the discovery of DNA: Within the nucleus of our cells, is the ...

A cell's nucleus has to hold the entire genome. To do that, the DNA must be carefully arranged and compacted by proteins called histones into a complex known as chromatin. Now scientists have ...

COLD SPRING HARBOR, N.Y. (Nov. 30, 2010) --The nucleus of a cell contains its DNA and is the site where DNA replication, transcription, and RNA processing take place. Within the nucleus, nuclear ...

Ultimately, everything is governed by the laws of physics, including gene regulation. Why is it, then, that that the laws of physics are so sparingly consulted when biologists describe chromatin, that ...

The Dere lab specializes in kidney cancer and VHL (von Hippel Lindau) disease focused on understand fundamental aspects of how non-chromatin functions of chromatin modifiers contribute to oncogenesis.