Iridoids are a widespread and evolutionarily ancient class of plant secondary metabolites belonging to the terpenes. They ...

We have many things in common with one another, but there are also things about each of us that are unique, like our fingerprints, our genome, and our gut microbiome. We carry trillions of microbes in ...

One of the most revolutionary discoveries of the century, the CRISPR gene-editing system is built on a bacterial defense mechanism that allows scientists to make precise edits to DNA. Now scientists ...

Researchers have solved the X-ray crystal structure of the enzyme that makes obafluorin -- a broad spectrum antibiotic agent made by a fluorescent strain of soil bacteria. This new class of ...

Researchers from Queen Mary University of London's School of Biological and Behavioral Sciences, using the simple fission ...

Epigenetic drug discovery and development programs have attracted much attention and investment in recent years. This is driven by the potential to develop novel therapeutic strategies that can ...

Similar to Alzheimer's disease, the hereditary disease spinocerebellar ataxia type 17 (SCA17) leads to the destruction of brain nerve cells and the premature death of patients. The exact mechanisms of ...

Study in fission yeast revealed a key role for a set of enzymes called agmatinases, which break down the metabolite agmatine into polyamines.

Understanding how antibiotic scaffolds are constructed in nature can help scientists prospect for new classes of antibiotics through DNA sequencing and genome mining. Researchers have used this ...