A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they ...

How would you identify the protein that serves as a connector between DNA helicase and pol-a/primase? A simple yet often effective approach is to find proteins that directly bind to both enzymes.

DNA replication is one of the most basic processes ... Meanwhile, as the helicase separates the strands, another enzyme called primase briefly attaches to each strand and assembles a foundation ...

Our cells prevent this excessive shortening by adding telomeric DNA to the ends of chromosomes ... telomerase and the ...

which disabled CST-Polα-primase, he produced a gel that did not fit the established model. The expected fill-in synthesis was incomplete. “Regular replication of the telomere was supposed to keep up ...