The fragments of newly synthesized DNA along the lagging strand are ... in the 5'-to-3' direction, and replication is always continuous along the leading strand and discontinuous along the lagging ...
DNA replication is a tightly controlled ... a key difference between the functions of the leading strand clamp loader (CTF18-RFC) and the lagging strand clamp loader (RFC) and illuminates an ...
Replication is the ... same time by using each unwound strand from the original DNA double helix as a template. One of these original strands is called the leading strand, whereas the other ...
For the first time, scientists have captured the exact moment DNA begins to unravel, shedding light on a fundamental chemical process that enables DNA to serve as the blueprint for life. A recent ...
Using a microscope slide as an anchor, we tethered DNA to a bead and stretched it with a flow of solution. We tracked how the position of the bead changed as the replication machinery went to work.