For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event ...

Scientists have captured the first detailed 'molecular movie' showing DNA being unzipped at the atomic level -- revealing how cells begin the crucial process of copying their genetic material.

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For ...

Scientists at the University of Leicester have captured the first detailed "molecular movie" showing DNA being unzipped at the atomic level – revealing how cells begin the crucial process of copying ...

The discovery, published in the peer-reviewed journal Nature, is stated to have far-reaching implications, helping us to ...

Understanding the process of replication and transcription of mtDNA ... "While mtDNA is much smaller than nuclear DNA, it plays a crucial role in life forms through energy production.

Replication of DNA DNA replication is the process by which a cell makes an identical copy of its DNA. Gene expression Only a fraction of the genes possessed by any particular cell will be expressed.

These obstacles perturb normal DNA replication by slowing or stalling replication fork progression, a process known as replication stress. High intrinsic replication stress is a hallmark of cancer.

Understanding the process of replication and transcription ... contributions to the understanding of mitochondrial DNA replication and mitochondrial disease. With years of dedicated research ...

We employ fully reconstituted yeast and human DNA replication systems to investigate the structure and biochemical mechanism of the eukaryotic replication machinery. A particular focus of the lab is ...