CCNs are a family of extracellular matrix proteins that regulate diverse aspects of cellular functions, and are involved in inflammation and tissue repair. Deregulation of CCN proteins is associated ...

Scientists at the University of Helsinki have found an essential factor from the extracellular matrix that regulates functionality of the breast tissue for instance during pregnancy. Extracellular ...

The matrix metalloproteinases (MMPs) comprise a family of zinc-dependent endopeptidases that consist of more than 21 human MMPs and numerous homologues from other species. They can be divided into ...

New images are providing the first visual evidence of a long-postulated physical link by which genes can receive mechanical cues from its microenvironment. Created by integrating six different imaging ...

Tissue engineering and regenerative medicine have made remarkable strides in developing strategies to repair and regenerate tissues affected by disease, ...

In his PhD research at Utrecht University and UMC Utrecht, Marc Falandt developed biomaterials whose properties can be adjusted even after they have been 3D-printed, effectively adding a fourth ...

FKBP65 (65-kDa FK506-binding protein) is an endoplasmic reticulum (ER)-localized peptidyl-prolyl cis-trans isomerase predicted to play a role in the folding and trafficking of secretory proteins. In ...

We applied swim flume-mediated exercise during zebrafish caudal fin regeneration to explore mechanical loading impacts on a robust model of organ regeneration. Exercise initiated during but not after ...

Biofilms of the fungus Candida albicans produce extracellular matrix that confers such properties as adherence and drug resistance. Our prior studies indicate that the matrix is complex, with major ...