Signet cell cancer is a rare type of cancer that mostly starts in the glandular cells. It is also called signet ring cell cancer. Nearly 57 out of 100 (57%) of all signet cell cancers start in the ...

Another key regulator is SOX10, which is required for the gereration of Schwann cell precursors from the neural crest. Understanding the signals that regulate the appearance of glial ...

The increasing implication of glial cells in neurodegenerative diseases makes them an appealing addition to iPSC-based model systems for investigating disease mechanisms. Over the last decade, Dr.

This in vitro reprogramming method has shown promise, but can have severe drawbacks, including immune rejection and cancer risks ... Zhang studies astrocytes because they are the most common glial ...

The Deneen Lab seeks to unlock the enigmatic biology surrounding glial cell development and function in the brain. Beginning with developmental gliogenesis, we identified the key transcriptional ...

In particular, 25-hydroxycholesterol (25-OHC) has been shown to contribute to arteriosclerosis, cancer development ... of 25-OHC in inducing cell death, particularly in glial cells.