In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular ...

Extended Lymph Node Dissection for Gastric Cancer: Who May Benefit? Final Results of the Randomized Dutch Gastric Cancer Group Trial Circulating cytokines, hormones, and growth factors control all ...

A multinational research team led by researchers at Institute of Science Tokyo, RIKEN, and the University of Toronto has ...

Researchers report a drug discovery strategy using tailor-made cyclic peptides to target β-arrestins, key regulators of ...

Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

Targeted modulation of certain intracellular signaling proteins could represent an exciting new approach to drug development.

Intracellular Delivery via EV-based Approach (IDEA) was designed to efficiently package and deliver non-fused intracellular proteins to cytoplasmic or nuclear compartments to be functional. As a ...

No matter where cancer cells grow in the human body, they are a threat to our health and our lives. But instead of treating them with chemotherapy or radiation—which have undesirable side effects—what ...

Plant immunity is largely initiated at the cellular level, with each cell capable of autonomous detection and response, while ...