For decades, scientists have fought cancer by developing small molecules to inhibit kinase enzymes. These enzymes play an important role in a host of cellular processes, including phosphorylation and ...
Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src ...
News Medical on MSN
AI-guided discovery of selective DGKα inhibitors to overcome checkpoint resistance in solid cancers
Insilico Medicine has developed a new class of small molecule inhibitors targeting diacylglycerol kinase alpha (DGKα) designed to restore T cell function and overcome resistance to immune checkpoint ...
AZoLifeSciences on MSN
Elusive kinase state explains how cells achieve efficient signaling
Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src ...
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