Mounting evidence links infections to a greater risk of dementia, and vaccination to neuroprotection. What underlies this relationship? In a preprint posted to Research Square on January 13, ...

When microglia wind up with a belly full of lipid droplets, it’s a sign that the cells are rallying, perhaps in vain, to a neurodegenerative threat. But according to a study published July 10 in Cell ...

New research suggests that compulsive behavior may be less about willpower failure and more about inflammation quietly disrupting the brain’s reward and habit circuits. While the idea of “hidden brain ...

Microglia are known to play an important role in Alzheimer's disease, but exactly what they do has remained a mystery. Scientists in the Bart De Strooper Lab at the VIB-KU Leuven Center for Brain & ...

Microglial activation is a determining factor that allows amyloid-beta accumulation to drive reactive astrogliosis, amplifying inflammatory responses in the brain. This was the conclusion of a study ...

Researchers have identified that microglia first help spread Alzheimer’s disease pathology across the brain and then activate to limit its neurodegenerative effects. Researchers from the VIB-KU Leuven ...

In this interview, Dr. Tilman explains the functions of iPSC-derived microglia and their relevance to conditions like Alzheimer’s and other neurodegenerative diseases. Microglia are the primary immune ...