Microfluidic chips that mimic human livers are better at predicting whether a drug is toxic to the liver than conventional animal models used in preclinical experimentations, claims a new study from ...
Animal testing isn’t just ethically questionable—it’s actually not that effective. Several biotech firms are developing technology that could change that. When 4,000 beagles destined for animal ...
A Delhi RML Hospital surgeon has warned that a common food parents consider healthy may raise fatty liver risk in children.
BOSTON--(BUSINESS WIRE)--Emulate, Inc. announced today that it has entered into a Cooperative Research and Development Agreement (CRADA) with the U.S. Food and Drug Administration’s (FDA) Office of ...
Lorna Ewart has long been frustrated by the mismatch between animal and human toxicity data. All too often preclinical studies in rats and dogs will suggest a drug is safe, only for clinical trial ...
The COVID-19 pandemic and a ban on non-human primate (NHP) exportation by China have dramatically altered the landscape of NHP use in US biomedical research. 1 The worsening NHP shortage along with ...
Address childhood obesity and diet, urge hepatologists as fatty liver, once an adult disease, is now affecting teenagers ...
The scientists used their chips to study the effects of drugs such as TAK-875 on liver health, mitochondrial function (red) and reactive oxygen species (cyan). This material relates to a paper that ...
Researchers are increasingly turning to organ-on-a-chip technology for drug testing and other applications. In a clean room in his lab, Sean Moore peers through a microscope at a bit of intestine, its ...
Inspired by hepatic lobules, a novel artificial liver was developed by assembling morphological cell sheets with high accuracy in terms of cell type, density, and distribution. By simulating the ...