New genetic research has identified a direct causal chain connecting the microorganisms in the human digestive tract to the ...

New genetic evidence links higher BMI and IBD to hidradenitis suppurativa risk, while smoking remains unclear. Read more.

Mendelian randomization is not affected by the confounding inherent in observational studies but it does rely on several assumptions, which can be hard to test Mendelian randomization can provide a ...

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Mendelian randomization is a study design that uses genetic variants as instrumental variables to test the causal effect of a (non-genetic) risk factor on a disease or health-related outcome. Since ...

Data included more than a million participants to find that Alzheimer's risk was up to 76% lower in these cases.

By comparing people who had these special genes to those who didn’t, the team found that even a small drop in ...

A new study published in the Journal of American Medical Association showed that higher body mass index (BMI) and an ...

Coffee is alternately championed and derided for its health effects. A new study introduces the genetics of caffeine metabolism into the conversation. In the ongoing battle over the benefits or risk ...

Studies have linked psoriasis and higher weight, but the causal relationship between the two has been unclear. What triggers what? Or could other underlying reasons explain the connection? "Higher BMI ...