Common symptoms that palliative care teams see in patients with metastatic breast cancer include pain, menopausal symptoms, fatigue, shortness of breath, nausea and appetite loss, constipation or diarrhea, emotional distress, sleep problems, and lymphedema.

Older Americans with metastatic breast, colorectal, lung, or prostate cancer are spending an increasing amount of time in the healthcare system, driven mainly by treatments, tests, and clinician visits. The number of healthcare contact days rose between 2008 and 2019, with a notable jump in the ambulatory visits from 2016 onward.

People living with metastatic breast cancer have more treatment options today than ever before. At Fred Hutch Cancer Center, we provide the latest in evidence-based care, including a wide range of supportive care services, to help you thrive while living ...

Clinical trials continue to shape metastatic breast cancer treatment, making therapies safer, more tolerable, and more effective. Investigators rely on data generated through each trial phase to determine whether new approaches offer meaningful benefit.

Overall, tucatinib add-on to first-line maintenance therapy for HER2-positive metastatic breast cancer delayed progression by 8.6 months.

1. Brenner A, Youssef M, Kumthekar P, et al. Rhenium (¹⁸⁶Re) obisbemeda (rhenium nanoliposome, ¹⁸⁶RNL) for the treatment of leptomeningeal metastases: phase 1 dose escalation study results. Abstract presented at: San Antonio Breast Cancer Symposium; December 9-12, 2025; San Antonio, Texas.

A University of Kentucky Markey Cancer Center study reveals how prostate cancer cells adapt their metabolism to thrive in bone tissue, offering a potential new treatment target for patients with advanced disease.

Hormone receptor (HR)–positive metastatic breast cancer is a type of breast cancer that has metastasized (spread) beyond the breast to other areas of your body. Metastatic breast cancer is also called advanced or stage 4 breast cancer. “HR-positive ...

What Is Metastatic Endometrial Cancer? Metastatic endometrial cancer is when cancer that starts in the lining of the uterus (endometrium) spreads to other parts of the body. Your doctor may call it stage IV endometrial cancer or advanced metastatic uterine ...

Tukysa, combined with Herceptin and Perjeta, extends progression-free survival in HER2+ metastatic breast cancer, showing benefits across various patient subgroups. At the 2025 SABCS, researchers presented findings with the potential to meaningfully affect breast cancer treatment and patient care.