Germ cell fate decisions are poorly understood, despite their central role in reproduction. One fundamental question has been whether germ cells are regulated to enter the meiotic cell cycle (i.e., ...

The nucleus is surrounded by the nuclear envelope (NE), which is formed by two juxtaposed membranes, termed the inner and outer nuclear membranes. A protein meshwork of intermediate filament proteins ...

We’ve all seen the movie. The sister chromatids hover at the metaphase plate, and then suddenly break apart and race toward the spindle poles. The suddenness of the event is striking: there can be ...