Semiconservative replication was not the only model of DNA replication proposed during the mid-1950s, however. In fact, two other prominent hypotheses were put also forth: conservative replication ...

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

Researchers at the Center for Embryology and Healthy Development (CRESCO) aim to find out why so many early embryos fail in ...

Scientists have provided the most detailed account yet of the earliest stages of DNA replication, an essential process for ...

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

Using cutting-edge cryo-electron microscopy, scientists at the University of Leicester have captured the first detailed “molecular movie” showing DNA being unzipped at the atomic level. The movie ...

Conjugation is a form of horizontal gene transfer that allows the exchange of genetic material between two organisms or cells. In this article, we discuss the mechanism of conjugation and how ...

DNA helicases are essential during DNA replication because they separate double-stranded DNA into single strands, allowing each strand to be copied. We recorded multiple snapshots showing how this ...

This new study provides definitive evidence about how these secondary DNA structures can pose physical barriers to DNA replication machinery ... provided a working model. "Our study showed ...