On the Eagles' end, their weakness has been turnovers. Philadelphia has four games this year with two or more turnovers and the Eagles have gone 0-4 in those games. If any defense out there can take advantage of that, it's a Bills unit that has forced 20 turnovers this year, which ranks in the top eight in the NFL.

Can Trevor Lawrence continue his hot streak against the rival Colts? Will Derek Stingley Jr. get another pick-six? Our analysts provide bold predictions for Week 17 of the 2025 NFL season.