Degenerative aortic stenosis (AS) has become the most common valvular heart disease and the definitive treatment of symptomatic, severe AS is surgical valve replacement. In the absence of symptoms, ...

Observational studies suggest that conventional right ventricular apical pacing may have a deleterious effect on left ventricular function. In this study, we examined whether biventricular pacing is ...

Group 3 – Severely impaired relaxation 1 (3.6%) 2 (11.1%) 7 (38.9%) 8 (44.4%) Values are number of subjects (%). Impaired relaxation (group 1) indicates low age-specific E:A and normal E:E'; elevated ...

Heart failure is a complex clinical syndrome affecting around 70 million individuals globally. It has a prevalence of 2% in ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Patients with abnormal diastolic function (when the heart is relaxed and expanded) in the left ventricle of the heart have a substantially lower maximum capacity for exercise, according to a new study ...

Avoiding Peg-Filgrastim Prophylaxis During the Paclitaxel Portion of the Dose-Dense Doxorubicin-Cyclophosphamide and Paclitaxel Regimen: A Prospective Study This was a multicenter study of all ...

In contrast to HF with reduced EF, where events (e.g., myocardial infarction) often signal the onset of cardiac dysfunction and symptoms, this is not the case in HF with normal EF, which starts ...