Loss of function of multiple ALS-associated RNA-binding proteins leads to reduced UNC13A expression through two distinct mechanisms: TDP-43 loss causes cryptic exon inclusion and mRNA destabilization, ...
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) can have the same genetic cause, a discovery that won two neurogeneticists a portion of the 2026 Breakthrough Prize in Life Scienc ...
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Amyotrophic Lateral Sclerosis (ALS): Early symptoms, root causes, and the science behind motor neuron decline
Amyotrophic Lateral Sclerosis (ALS), commonly known as Lou Gehrig’s disease, is a rare yet devastating neurological disorder that progressively weakens the body’s voluntary muscles. It occurs when ...
Researchers at the University of Toronto (U of T) have uncovered new insights on the genetic causes of Amyotrophic Lateral Sclerosis (ALS), which is also known as Lou Gehrig's disease. These findings ...
A Northwestern Medicine study has shed light on a critical molecular mechanism underlying amyotrophic lateral sclerosis (ALS), according to findings published in the journal Neuron. Subscribe to our ...
The exact genetic and epigenetic cause of the sporadic form of amyotrophic lateral sclerosis (ALS), which affects approximately 90% of patients, are largely unknown. Previous work found that ...
The Longitude Prize on ALS Discovery Award recognises 'Decode ALS', an international consortium led by Sheffield scientists, to advance a pioneering ...
MRI is a diagnostic test that doctors use to diagnose and track the progress of amyotrophic lateral sclerosis (ALS). ALS is a progressive disease that damages nerve cells in the brain and spinal cord.
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