Due to the 4-hour maturation half-life of the Timer protein's blue-to-red chromophore, we can detect reactivated or recently silenced proviruses with high sensitivity using Timer fluorescence.

The human immunodeficiency virus (HIV) is a retrovirus that integrates into the human genome. This intact, integrated genome is referred to as a provirus and represents a latent or dormant form of the ...

Advancements in HIV/AIDS research, drug development and clinical practice since the 1980s have made it possible for people living with HIV to lead long, productive lives and keep the virus in check at ...

Researchers at Johns Hopkins Medicine have reported evidence that standard chemotherapeutic drugs may selectively suppress HIV-infected immune cell clones, an observation that could inform future ...

A team of researchers studying HIV have created a test that they say will allow clinicians and scientists to better track efforts to cure the disease. Most HIV drugs attack the active virus, which ...

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In a person living with HIV, proviruses—strands of HIV DNA—are typically integrated into the T cell genome and become a permanent part of the cell's genetic makeup. This integration enables the ...