When people think of kidney disease, they usually think about problems with how the body removes waste—not about skin issues.

The chronic disease is unpredictable and often has subtle symptoms that are easily missed or attributed to other ailments.

Medically reviewed by Casey Gallagher, MD Itchy skin (pruritus) without a rash may be caused by dry skin, allergies, bug ...

Kidney disease, especially in the advanced stages, can cause itching without a rash. If a person knows they have kidney problems and start to develop itching skin, they should contact a doctor.

Last summer, infectious disease specialist Gregory Poland saw a patient at the Mayo Clinic in Rochester, Minnesota, who had a fever, a rash, kidney failure, and—despite seeing several doctors—no ...