In the inflamed joints of rheumatoid arthritis, CD4+ T lymphocytes accumulate lipid droplets that make them vulnerable and promote their death, thereby amplifying joint inflammation. A study led by ...

Rheumatoid arthritis (RA) is a chronic autoimmune disease in which the immune system mistakenly attacks the lining of the joints (the synovium), causing pain, swelling, and progressive damage.

Millions of people around the world suffer from rheumatoid arthritis, an autoimmune disorder that causes debilitating joint swelling and pain. Researchers have been looking for ways to identify those ...

One genetic mutation may transform the way we treat rheumatoid arthritis, a disease that will affect an estimated one percent of the world. York University researchers have identified a mutation in ...

Research led by York University's Faculty of Health reveals how a specific mutation in a protein called TRAF1 can shut down an overactive immune response, dramatically reducing inflammation in mice.

Learn how aging with rheumatoid arthritis presents challenges and comorbidities, and why aggressive treatment remains crucial ...

Announcing a new article publication for BIO Integration journal. In recent years, phytochemicals and medicinal plants have ...

Discover how Treg cell therapies rethink precision medicine for autoimmune diseases like type 1 diabetes, MS, and transplant rejection.

From birth-month signatures to global climate gradients, emerging evidence indicates that seasonal light, temperature, and ...

The IGFL2 gene encodes a cytokine found in primates, which are closely related to humans. In the joint tissue of people with rheumatoid arthritis, peripheral helper T (Tph) cells express IGFL2, which ...