Fred Hutch

Glitch to switch: Turning spliceosome mutations into immune targets

Think of the bone marrow as the body’s factory for blood and immune cells. In myelodysplastic syndromes (MDS), that factory breaks down—producing too few cells, and the ones that do roll off the line ...
ascopubs.org

Targeting the Tumour-Specific Spliceosome Through In Silico Virtual Screening for Discovery of New SF3B1 Small Molecule Inhibitors

Status of Bone Mineral Density Mammographic Breast Density and Serum Oestrogen and Calcium Levels: A Case-Control Study This is an ASCO Meeting Abstract from the 2018 World Cancer Congress Abstracts.
Nature

Distinct and convergent effects of SF3B1 mutations in human breast cancer

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...
Nature

Cancer-associated SF3B1 mutation K700E causes widespread changes in U2/branchpoint recognition without altering splicing

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...
ascopubs.org

Splicing factor 3B subunit 1A (SF3B1) mutations in lymphoid malignancies.

Relevance and specificity of the French CIAN LUNG cohort for clinical research analyses in lung cancer using real-world data. The efficacy of daprodustat compared to standard recombinant human ...