Cellular senescence occupies a pivotal position in cancer biology, acting as both a barrier against malignant transformation and a potential driver of ...

A new research paper, titled "In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers," was published on the cover of Aging Zoledronic acid ...

There is growing evidence that the appearance and texture of the skin that is altered during the aging process are considerably enhanced by the accumulation of senescent dermal fibroblasts. These ...

“Overall, this research could potentially aid in the development of anti-aging treatments for skin by preventing age-related changes through the regulation of SFRP4 expression in aging cells.” There ...

Cellular senescence is a state characterized by permanent cell-cycle arrest, increased expression of markers such as p16^INK4a and p21^CIP1/WAF1, elevated DNA damage signals (e.g., γ-H2AX) and a ...

According to the latest statistics from the National Cancer Institute, more than 60% of cancer patients are 65 or older and the median age at diagnosis is 66. In fact, age is the largest risk factor ...

If you are fit, it is easier to master life,” said Johanna Quaas, a 91-year-old woman from Germany. Johanna was speaking as an elite athlete. She started competing in her youth, went on a hiatus after ...

A new review was published in Volume 18 of Aging on May 30, 2026, titled "The love and hate relationship between cellular ...

Aging is a complex biological process characterized by the progressive decline of physiological integrity, leading to impaired function and increased vulnerability to disease. It is the strongest risk ...

“In the present study, we used multiple complementary approaches to evaluate the possible effects of zoledronic acid on cellular senescence.” Zoledronic acid has been found to reduce fracture risk and ...