New research suggests pain is not a simple signal of injury but a process that unfolds across nerves, spinal cord, and brain.

"One region in the thoracolumbar spinal cord was shown to relay noxious information into brainstem pain-related circuits, while the other spinal region in the lumbosacral spinal cord carried a broader ...

After a spinal cord injury, nearby cells quickly rush to action, forming protective scar tissue around the damaged area to stabilize and protect it. But over time, too much scarring can prevent nerves ...

A neural circuit hidden in an understudied region of the brain plays a critical role in turning temporary pain into pain that can last months or years, according to new University of Colorado Boulder ...

Scientists created a model of the human pain pathway in a dish by connecting four separate brain organoids. The feat should help them understand sensory disorders like those affecting pain perception.

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Stroke and spinal cord injuries can severely impair motor functions, and understanding how to promote recovery is a critical challenge. While damaged neurons in the brain and spinal cord have limited ...

A research team from the University of Cologne has shown how zebrafish can rebuild their nerve pathways and restore their locomotor function after a spinal cord injury. Specialized connective tissue ...