We've long assumed our species evolved from a tidy, single stream of ancestors. But life on Earth is never quite so straightforward, especially not when it comes to the most socially complex species ...

To make a gene-editing tool more precise and easier to control, engineers split it into two pieces that only come back together when a third molecule is added. To make a gene-editing tool more precise ...

Researchers have found that splitting the gene editor used in traditional CRISPR technology creates a more precise tool that can be switched on and off, with significantly less chance of causing ...

A group of engineers at Rice University has devised a novel approach to enhance the precision and control of a gene-editing tool. This innovative method involves splitting the tool into two components ...

University of Zurich scientists demonstrated that they could reassemble and express large genes using a new dual adeno-associated viral (AAV) vector technology that depends on mRNA trans-splicing.

One problem in gene therapy is that not all genes transfer equally well into the target cells. Researchers have now developed a flexible method to transfer large genes efficiently and without ...

Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor Hirohisa Ohno (Department of Life Science Frontiers at CiRA) recently led a ...

In 2023, the US Food and Drug Administration approved the first gene therapy for Duchenne muscular dystrophy (DMD). But that therapy, Elevidys, can‘t replace the entire dystrophin gene, the absence of ...

HOUSTON – (Sept. 21, 2023) – To make a gene-editing tool more precise and easier to control, Rice University engineers split it into two pieces that only come back together when a third small molecule ...

Gene therapy currently represents the most promising approach for the treatment of hereditary diseases. Yet despite significant breakthroughs in recent years, there are still a number of hurdles that ...