A new study finds that at least one Archaea has surprisingly flexibility when interpreting genetic code, which goes against a ...

For decades, biology has relied on one central assumption: the genetic code is precise. DNA is transcribed into RNA, RNA is ...

Gene editing can repair mutations that prematurely halt protein synthesis, resulting in incomplete peptides that cause various diseases. However, other approaches achieve the same effect without ...

Translation termination takes place when one of three stop codons is recognized by a proteinaceous class 1 release factor (RF) in the A site of the ribosome. The RFs are bifunctional molecules, like ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...

It has long been assumed that there is only one 'canonical' genetic code, so each word means the same thing to every organism. Now, this paradigm has been challenged by the discovery of large numbers ...

A messenger RNA (mRNA) does more than provide ribosomes a template for creating a sequence of amino acids. It also conveys regulatory information, including so-called stop codons. But just as cars ...

The complete nucleotide sequence of the tapeworm Taenia solium mitochondrial DNA (mtDNA) has been determined. The sequence is 13,709 base pairs in length and contains 36 genes (12 for proteins ...

“This is the first real data point that looks at [stop codon reassignment] in an objective way to ask how common is it,” said Laura Landweber, a professor of ecology and evolutionary biology at ...