This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
Unlocking the therapeutic applicability of LNP-mRNA: chemistry, formulation, and clinical strategies
LNP as the novel drug delivery system enhancing mRNA therapeutic efficacy has been proved for its delivery ability. This review provides valuable insights into the current state-of-the-art of LNP mRNA ...
Adding a photocopier gene to mRNA vaccines could make them last longer and curb side effects. This article first appeared in The Checkup, MIT Technology Review's weekly biotech newsletter. To receive ...
In recent years, mRNA technology enabled the rapid development of vaccines to fight COVID-19, saving millions of lives. That same mRNA-powered approach to medicine—in which synthetic mRNA is ...
At the Mayo Clinic, Dr. Guifang Zhao is leading a new generation of regenerative medicine therapies that combine the ...
Vaccines that resemble viruses generally produce a stronger immune response, while mRNA versions are much quicker and cheaper to make. Now we are getting the best of both worlds, in the form of mRNA ...
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
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