As the body grows, the immune system starts losing its strength. Inside the weakening immune system, the populations of ...

Immune protection fades with time, and much of that decline traces back to the thymus. This small organ, located in front of the heart, trains new T cells and releases signals that help them survive.

New data highlight liver-encoded delivery of immune modulators as a strategy to mitigate age-related immune dysfunction.

WE have observed that repeated injections of reserpine induce atrophy of the thymus in adult and new-born rats (unpublished results). Since the thymus is known to play an important part in immune ...

As people age, their immune system function declines. T cell populations become smaller and can't react to pathogens as ...

The deterioration in immune function that occurs as an individual ages is thought to occur because the thymus involutes with age, causing a dramatic decrease in T cell output. New data generated by ...

MIT and Broad Institute researchers have developed an mRNA approach that temporarily programs liver cells to produce ...

The axolotl, a type of salamander that stays in the tadpole form throughout its life, is a master of regeneration. Axolotls have been observed to regrow several body parts, including limbs, eyes, and ...

The thymus is a specialised primary lymphoid organ that underpins the development and education of T cells. Here, immature progenitors undergo a tightly regulated series of events that not only ...

Researchers at MIT and the Broad Institute have found a way to overcome age-related immune system decline by temporarily programming cells in the liver to take over a critical immune system function: ...