Collagen, a protein found in bones and connective tissue, has been found in dinosaur fossils as old as 195 million years.

Peptide bond formation is one of the key chemical transformations in the field of prebiotic chemistry. It is regarded that peptides played an important catalytic role in the formation of other ...

A peptide bond is a chemical bond formed between two molecules when the carboxyl group of one molecule reacts with the amino group of the other molecule, releasing a molecule of water (H2O). This ...

The process of 'translation' in protein synthesis involves formation of a peptide bond between two amino acids that are attached to two distinct transfer RNAs (tRNAs). For long, scientists have ...

The process of “translation” in protein synthesis involves formation of a peptide bond between two amino acids that are attached to two distinct transfer RNAs (tRNAs). For long, scientists ...

Although peptide bond formation has been widely established, obtaining oligopeptides in high yields requires catalysis, to overcome kinetic limitations, and activation of the amino acid monomers ...

To achieve this result, the team developed a new reaction for peptide bond formation, specifically the combination of an alpha-ketoacid and a hydroxylamine ligation.

Researchers have now come up with a metal-free approach in which they use a synthetic peptide called a foldamer to catalyze macrocycle formation with yields as high as 97% (Science 2019, DOI: 10. ...

The large subunit rRNA, in particular, is responsible for the peptidyl transferase reaction, which catalyzes the formation of peptide bonds between amino acids during protein synthesis. This discovery ...