Simon Says isn’t just a game, it’s a window into early HD! In this study, tiny thumb twitches reveal how attention slips ...

Participants in a PET study received the tracer, then gave it time to reach the brain. Then they laid in a scanner that took ...

Scientists used 3D mini-brains grown from stem cells to study Huntington’s disease. They found early developmental changes ...

On June 2, 2025, uniQure shared that they’re aligned with the FDA about moving forward with their HTT-lowering gene therapy, AMT‑130. If the next round of results from their ongoing trial continues to ...

Picture a quiet neighborhood. Things used to run smoothly here. Kids played outside, front yards were mowed, and the neurons — the longtime residents — looked out for one another. But lately, fires ...

Minocycline: the end of the road? DOMINO clinical trial result: minocycline doesn’t slow down HD and shouldn’t be studied in larger trials.

TRACK-HD reveals significant changes in pre-symptomatic HD mutation carriers and patients The one-year report from the TRACK-HD study demonstrates a number of changes in pre-symptomatic HD-mutation ...

Scientists tested a new tool to measure harmful HTT protein in HD. It wasn’t perfect, but offered key insights to guide better tools already in the works. A big step toward tracking HD non-invasively, ...

The HDBuzz team recently convened in Palm Springs, California, along with hundreds of other scientists from all over the globe, for the 19th Annual HD Therapeutics Conference, hosted by the HD ...

Dr. Leora Fox works at the Huntington's Disease Society of America, which has relationships and non-disclosure agreements with pharmaceutical companies, including Wave Life Sciences and Roche. Rachel ...