Lysosomes are dynamic organelles that receive membrane traffic input from the secretory, endocytic, autophagic and phagocytic pathways. They can also fuse with the plasma membrane. Live-cell imaging ...

Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases ...

Scientists have pinpointed a protein in lysosomes that is involved in recycling a crucial fatty component of cell membranes to keep cells healthy. Researchers at Duke-NUS Medical School and colleagues ...

Long recognized as the cell’s recycling depot, a new study has found lysosomes act as signaling hubs that coordinate metabolism and longevity by communicating signals across tissues. According to a ...

Scientists at Baylor College of Medicine, the Howard Hughes Medical Institute (HHMI) and collaborating institutions report in the journal Nature Cell Biology that lysosomes in roundworms produce ...

Scientists are no longer just cataloging the damage that comes with age, they are starting to rewire the machinery inside ...

Lysosomes are thought of as cellular organelles that play an important role in recycling proteins and maintaning cells by breaking down stuff that isn’t needed. But new research has found that ...

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children's Research Hospital scientists recently ...

New research, published today in the journal Science, shows how lysosomes - organelles that act like cells' waste disposal system - respond to stress by becoming abnormally bloated, a process called ...

The lysosome was once thought of as the trash can of the cell, a dead-end destination where cellular debris was sent for disposal. But a growing body of research shows that this enzyme-filled vesicle ...