Netrin1 is a protein that was first characterized for its axon guidance activities during embryonic development. The netrin family has been shown to play many critical roles in developmental and ...

A new drug-free, minimally invasive intervention targets the root cause of progressive loss of neural function in spinal muscle atrophy (SMA), an inherited neuromuscular disease. An intervention, ...

New research from the University of St Andrews, the University of Copenhagen and Drexel University has developed AI ...

Researchers have uncovered a surprising new role for netrin1, a crucial protein in neural development, as a regulator that limits bone morphogenetic protein signaling in the developing spinal cord.

Spinal cord injury (SCI) causes structural damage to neural circuits, which in turn leads to sensory and motor dysfunction. Transplantation of neural precursor cells/stem cells provides a potential ...

PITTSBURGH, Feb. 5, 2025 – A new drug-free, minimally invasive intervention targets the root cause of progressive loss of neural function in spinal muscle atrophy (SMA), an inherited neuromuscular ...

Spinal muscular atrophy affects the development of the nervous system more profoundly than was previously thought, a new ...

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have uncovered an unexpected role for the molecule netrin1 in organizing the developing spinal ...

A phase 1 clinical trial demonstrated the long-term safety and feasibility of neural stem cell transplantation for treating chronic spinal cord injuries. The corresponding study was published in Cell ...

Traumatic spinal cord injury (SCI) causes partial or complete loss of sensory, motor, and autonomic functions below the site of injury. Patients suffering from SCI may experience severe morbidity and ...