Even with eight injured players, third-down struggles and troublesome redzone offense in Chapel Hill, 49ers coach Biff Poggi ...

The San Francisco 49ers picked up their first loss of the season, falling 23-17 to the Minnesota Vikings in Week 2. A special teams error, two turnovers (interception and fumble) and two turnovers ...

The 49ers have announced that RB Christian McCaffrey has been placed on IR and S Tracy Walker III has been elevated from the practice squad. The San Francisco 49ers announced that the team has ...

The San Francisco 49ers take their 1-0 record to the road against the Minnesota Vikings on Sunday. San Francisco easily took care of the Aaron Rodgers and the New York Jets at home in the season ...

Just two games into the season, the Rams (0-2) are approaching desperate times as they prepare to face the San Francisco 49ers (1-1) Sunday afternoon at SoFi Stadium. The list of issues thus far for ...

49ers star tight end George Kittle was not in attendance for Thursday's practice session. According to ESPN's Adam Schefter, Kittle is experiencing tightness in his hamstring. The 49ers are taking ...

The loss to the Minnesota Vikings is getting worse for the San Francisco 49ers. Star wide receiver Deebo Samuel sustained a calf strain in the game and is expected to be out for a "couple weeks ...

The San Francisco 49ers have one of the most well-built rosters in football. San Francisco made a run to the Super Bowl last season, although it ended up losing to the Kansas City Chiefs.

Then, nothing. It seems obvious that the San Francisco 49ers do not want to trade Aiyuk. No contract agreement has been reached. But the 49ers are ready for him to get back to practice.