Compromised antigen presentation ranks among the top mechanisms that render cancers non-immunogenic (non-responsive to immune ...

This paper investigates how isoform II of transcription factor RUNX2 promotes cell survival and proliferation in oral squamous cell carcinoma cell lines. The authors used gain and loss of function ...

SkinJect Inc. a wholly owned subsidiary of Medicus Pharma Ltd, is a development stage, life sciences company focused on commercializing novel, non-invasive treatment for basal cell skin cancer using ...

Several components of the hedgehog (Hh) pathway are crucial to basal cell carcinoma (BCC) tumorigenesis. Primary cilia have emerged as key organelles in Hh signal transduction in mammalian systems ...

Now visualized using cryo-electron microscopy, the carrier’s lock-like mechanism could be the key to tackling diseases like cancer, diabetes ... it needs to be transferred inside the cell’s ...

A new discovery could pave the way for more effective cancer treatment by helping certain ... to improve their ability to slip through cell membranes by passive diffusion. But the new strategy ...

researchers delivered 7.7 to 22.3 times more of the drug inside cancer cells, making the treatment up to 23 times more potent than before, according to the study published April 17 in Cell.

they were able to deliver between 7.7 and 22.3 times more of the drug into cancer cells – making the treatment up to 23 times more effective, according to a study published today (April 17) in Cell.

Researchers found pyronaridine disrupts an enzyme critical to cellular division and can cause cancer cell death. Additionally, the drug has not been shown to cause significant adverse events in ...

Results showed tarlatamab demonstrated statistically significant and clinically meaningful improvement in overall survival vs standard of care therapy. Topline data were announced from a phase 3 ...

1State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School and Hospital of ...