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When you have various aches and pains, it can be challenging to decide which over-the-counter pain reliever is best matched for your affliction — Advil, Aleve, Tylenol, Motrin?

Alternating antipyretics: antipyretic efficacy of acetaminophen versus acetaminophen alternated with ibuprofen in children. Clin Pediatr (Phila) 2008;47:907–11.

People often use the wrong painkiller or take too much too quickly, increasing the risk of side effects, say pharmacists. Here are safer and more effective ways to take drugs like Advil and Tylenol.

Alternate between NSAIDs and acetaminophen to manage major pain and reduce side effects. If you're suffering from the flu or nursing a new injury and need strong and steady pain relief, switching ...

Alternating between acetaminophen and an NSAID like ibuprofen can be safe and effective for pain management. 9. Alternate between NSAIDs and acetaminophen to manage major pain and reduce side effects.

People often use the wrong painkiller or take too much too quickly, increasing the risk of side effects, say pharmacists. Here are safer and more effective ways to take drugs like Advil and Tylenol.

Do not guess their weight — acetaminophen and ibuprofen can be dangerous when given in the wrong dose. Check with your pediatrician before giving your child any pain relievers.

Photo by simpson33 / Getty Images Alternate Tylenol and Advil One of the most effective ways to deal with the symptoms of a flu is using Tylenol, Advil or other other-the-counter pain relievers.