Many patent applicants currently face difficulty in obtaining antibody claims because of written description and enablement ...

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Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these ...

Studies have shown that certain beads carry more antigen than other beads, thus rendering detection of some antibodies more sensitive than others. [12] Furthermore, density differences between a ...

Additionally, detection of both anti-MHC class I and class II antibodies was problematic. The predominant problem underlying class distinction arises from the distribution of HLA antigens.

The purified antibody was characterized for conjugation specificity and efficiency and used in a functional antigen-binding assay. To quantify the amount of biotinylation on the rat anti-HRP ...

The new research, described in a new study published in the Proceedings of the National Academy of Sciences, focuses on two powerful antibodies ... with sugar-binding sites, while hu1B7 prevents ...

Conclusions: We developed an AI model to simulate antigen-antibody binding and identify mutations for affinity enhancement. These predicted mutations were subsequently validated through experimental ...