we aimed to determine the role of recombinant PIBF1 in the alleviation of lupus nephritis (LN) in MRL/MpJ-Faslpr/J (MRL/lpr) mice. Methods MRL/lpr mice were ovariectomized at 6 weeks of age, and ...

Other animal models that have been used to study systemic lupus include the BXSB and MRL/lpr mice, and the naturally occurring syndrome of lupus in dogs. The familial occurrence of systemic lupus was ...

Protein was collected for subsequent analysis. Results We found that metformin administration improved renal function in MRL/lpr lupus-prone mice, measured by decreased urea nitrogen and urinary ...

autoimmunity and disease development in lupus-prone mice. Methods Mitochondria were evaluated in peripheral blood lymphocytes (PBL) of 38 SLE patients and 21 healthy controls and mouse models by flow ...

Background The 16/6 idiotype was shown to induce experimental lupus in naïve mice 1. Its ability to induce brain specific disease was not evaluated before. Objectives We assessed the behavior and ...

A new "groundbreaking" treatment for lupus has given doctors and patients hope that it could end the need for lifelong medication. Three patients have received CAR T-cell therapy for the most ...

"The launch of the DREAM completes our vision of the Lupus Nexus," said Devon Kelly, Director, Lupus Nexus, Lupus Research ...

A new "groundbreaking" treatment for lupus has given doctors and patients hope that it could end the need for lifelong medication. Three patients have received CAR T-cell therapy for the most serious ...

Yes, a dermatologist can diagnose lupus. They specialize in treating conditions that affect the hair, skin, and nails, such as autoimmune diseases like lupus. They can work with you to put ...

greatly reduced atrophied brain matter in mice with the disease. The team behind the vaccine, whose members include researchers from Kyoto University, said its experiments with the mice showed ...