Creation of a permanent lesion in the subthalamic nucleus (STN) might provide an alternative approach to deep brain stimulation (DBS) in the treatment of Parkinson disease when the latter ...

Using Parkinson’s disease as a case study, we review here how computational models are a crucial tool for taming this complexity, across causative mechanisms, consequent neural dynamics and treatments ...

Parkinson’s disease is known for symptoms like tremors, rigidity and slowness of movement. There are non-motor symptoms as ...