To investigate these processes, the researchers used spatial transcriptomics to create maps of nine tissues – hippocampus, ...

This valuable study examines how different exercise training intensities affect intestinal barrier function and gut microbiota composition over a 6-week period in mice. The evidence supporting the ...

A recent study published in Progress in Neuropsychopharmacology & Biological Psychiatry suggests that cannabidiol (commonly ...

As the science stands, the vast majority of the roughly eight million people in South Africa living with HIV will have to get ...

Highly effective treatments for HIV have existed since the mid-1990s. But while these treatments keep people healthy, we do not yet have a safe and scalable way to completely rid the body of the virus ...

IND-enabling, nonclinical toxicology studies demonstrated i.v. administration without sustained induction of hallmark biomarkers of cytokine release syndromes, possibly due to passive targeting to ...

Encouraging Preclinical Data: Decoy20 has produced efficacy in preclinical studies across a variety of tumor types and in combination with four different classes of existing drugs, demonstrating both ...

These should be assessed and developed in mouse models; however, in most cases, immunological parameters are assessed in lymphoid organs such as the spleen or pancreatic lymph node, which are not ...

The in vivo cell therapy seed Carisma Therapeutics planted with Moderna in 2022 is starting to sprout. | The in vivo cell ...

The aging and failure of cells that occurs when the liver is damaged can spread to other organs, suggests a new study in mice ...

Why do mice have tails? The answer to this is not as simple as you might think. Research has shown that there's more to the humble mouse tail than previously assumed. Using a novel experimental setup ...